USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P49720 USC-OGP 2-DE database:  P49720 P49720 General information about the entry View entry in simple text format Entry name PSB3_HUMAN Primary accession number P49720 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Proteasome subunit beta type-3; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=Proteasome chain 13; AltName: Full=Proteasome component C10-II; AltName: Full=Proteasome theta chain;. Gene name Name=PSMB3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0547: pI=5.92; Mw=23369 Cross-references UniProtKB/Swiss-Prot P49720; PSB3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PSB3_HUMAN Primary accession number P49720 Secondary accession number(s) P31147 Q0P6J7 Q96E27 Sequence was last modified on  May 10, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 179) Name and origin of the protein Description RecName: Full=Proteasome subunit beta type-3; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=Proteasome chain 13; AltName: Full=Proteasome component C10-II; AltName: Full=Proteasome theta chain; Gene name Name=PSMB3 Encoded on Name=PSMB3 Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D26598; BAA05645.1; -; mRNA EMBL BC013008; AAH13008.1; -; mRNA CCDS CCDS11328.1; -; . PIR S55041; S55041; . RefSeq NP_002786.2; NM_002795.3; . UniGene Hs.82793; -; . PDB 4R3O; X-ray; 2.60 A; J/X=2-205 PDB 4R67; X-ray; 2.89 A; J/X/l/z=2-205 PDB 5A0Q; EM; 3.50 A; J/X=2-205 PDB 5GJQ; EM; 4.50 A; c/q=1-205 PDB 5GJR; EM; 3.50 A; c/q=1-205 PDB 5L4G; EM; 4.02 A; 3/W=1-205 PDB 5LE5; X-ray; 1.80 A; I/W=1-205 PDB 5LEX; X-ray; 2.20 A; I/W=1-205 PDB 5LEY; X-ray; 1.90 A; I/W=1-205 PDB 5LEZ; X-ray; 2.19 A; I/W=1-205 PDB 5LF0; X-ray; 2.41 A; I/W=1-205 PDB 5LF1; X-ray; 2.00 A; I/W=1-205 PDB 5LF3; X-ray; 2.10 A; I/W=1-205 PDB 5LF4; X-ray; 1.99 A; I/W=1-205 PDB 5LF6; X-ray; 2.07 A; I/W=1-205 PDB 5LF7; X-ray; 2.00 A; I/W=1-205 PDB 5T0C; EM; 3.80 A; AP/BP=2-205 PDB 5T0G; EM; 4.40 A; P=2-205 PDB 5T0H; EM; 6.80 A; P=2-205 PDB 5T0I; EM; 8.00 A; P=2-205 PDB 5T0J; EM; 8.00 A; P=2-205 PDBsum 4R3O; -; . PDBsum 4R67; -; . PDBsum 5A0Q; -; . PDBsum 5GJQ; -; . PDBsum 5GJR; -; . PDBsum 5L4G; -; . PDBsum 5LE5; -; . PDBsum 5LEX; -; . PDBsum 5LEY; -; . PDBsum 5LEZ; -; . PDBsum 5LF0; -; . PDBsum 5LF1; -; . PDBsum 5LF3; -; . PDBsum 5LF4; -; . PDBsum 5LF6; -; . PDBsum 5LF7; -; . PDBsum 5T0C; -; . PDBsum 5T0G; -; . PDBsum 5T0H; -; . PDBsum 5T0I; -; . PDBsum 5T0J; -; . ProteinModelPortal P49720; -; . SMR P49720; -; . BioGrid 111664; 99; . DIP DIP-33846N; -; . IntAct P49720; 32; . MINT MINT-5001041; -; . STRING 9606.ENSP00000225426; -; . BindingDB P49720; -; . ChEMBL CHEMBL2364701; -; . MEROPS T01.983; -; . iPTMnet P49720; -; . PhosphoSitePlus P49720; -; . SwissPalm P49720; -; . BioMuta PSMB3; -; . DMDM 20532411; -; . OGP P49720; -; . REPRODUCTION-2DPAGE IPI00028004; -; . EPD P49720; -; . MaxQB P49720; -; . PaxDb P49720; -; . PeptideAtlas P49720; -; . PRIDE P49720; -; . TopDownProteomics P49720; -; . DNASU 5691; -; . Ensembl ENST00000619426; ENSP00000483688; ENSG00000277791; . Ensembl ENST00000619951; ENSP00000483956; ENSG00000275903; . GeneID 5691; -; . KEGG hsa:5691; -; . UCSC uc002hqr.5; human; . CTD 5691; -; . GeneCards PSMB3; -; . H-InvDB HIX0030292; -; . HGNC HGNC:9540; PSMB3; . HPA HPA042775; -; . HPA HPA048147; -; . MIM 602176; gene; . neXtProt NX_P49720; -; . OpenTargets ENSG00000277791; -; . PharmGKB PA33885; -; . eggNOG KOG0180; Eukaryota; . eggNOG ENOG410XSC8; LUCA; . GeneTree ENSGT00550000074820; -; . HOGENOM HOG000090523; -; . HOVERGEN HBG004446; -; . InParanoid P49720; -; . KO K02735; -; . OMA YIEPVIA; -; . OrthoDB EOG091G0JTX; -; . PhylomeDB P49720; -; . TreeFam TF106216; -; . Reactome R-HSA-1169091; Activation of NF-kappaB in B cells; . Reactome R-HSA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; . Reactome R-HSA-1236974; ER-Phagosome pathway; . Reactome R-HSA-1236978; Cross-presentation of soluble exogenous antigens (endosomes); . Reactome R-HSA-174084; Autodegradation of Cdh1 by Cdh1:APC/C; . Reactome R-HSA-174113; SCF-beta-TrCP mediated degradation of Emi1; . Reactome R-HSA-174154; APC/C:Cdc20 mediated degradation of Securin; . Reactome R-HSA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; . Reactome R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; . Reactome R-HSA-180534; Vpu mediated degradation of CD4; . Reactome R-HSA-180585; Vif-mediated degradation of APOBEC3G; . Reactome R-HSA-187577; SCF(Skp2)-mediated degradation of p27/p21; . Reactome R-HSA-195253; Degradation of beta-catenin by the destruction complex; . Reactome R-HSA-202424; Downstream TCR signaling; . Reactome R-HSA-211733; Regulation of activated PAK-2p34 by proteasome mediated degradation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2871837; FCERI mediated NF-kB activation; . Reactome R-HSA-349425; Autodegradation of the E3 ubiquitin ligase COP1; . Reactome R-HSA-350562; Regulation of ornithine decarboxylase (ODC); . Reactome R-HSA-382556; ABC-family proteins mediated transport; . Reactome R-HSA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA; . Reactome R-HSA-4608870; Asymmetric localization of PCP proteins; . Reactome R-HSA-4641257; Degradation of AXIN; . Reactome R-HSA-4641258; Degradation of DVL; . Reactome R-HSA-5358346; Hedgehog ligand biogenesis; . Reactome R-HSA-5362768; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; . Reactome R-HSA-5607761; Dectin-1 mediated noncanonical NF-kB signaling; . Reactome R-HSA-5607764; CLEC7A (Dectin-1) signaling; . Reactome R-HSA-5610780; Degradation of GLI1 by the proteasome; . Reactome R-HSA-5610783; Degradation of GLI2 by the proteasome; . Reactome R-HSA-5610785; GLI3 is processed to GLI3R by the proteasome; . Reactome R-HSA-5632684; Hedgehog 'on' state; . Reactome R-HSA-5658442; Regulation of RAS by GAPs; . Reactome R-HSA-5668541; TNFR2 non-canonical NF-kB pathway; . Reactome R-HSA-5676590; NIK-->noncanonical NF-kB signaling; . Reactome R-HSA-5678895; Defective CFTR causes cystic fibrosis; . Reactome R-HSA-5687128; MAPK6/MAPK4 signaling; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-68827; CDT1 association with the CDC6:ORC:origin complex; . Reactome R-HSA-68949; Orc1 removal from chromatin; . Reactome R-HSA-69017; CDK-mediated phosphorylation and removal of Cdc6; . Reactome R-HSA-69229; Ubiquitin-dependent degradation of Cyclin D1; . Reactome R-HSA-69481; G2/M Checkpoints; . Reactome R-HSA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; . Reactome R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; . ChiTaRS PSMB3; human; . GeneWiki PSMB3; -; . GenomeRNAi 5691; -; . PRO PR:P49720; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000108294; -; . CleanEx HS_PSMB3; -; . ExpressionAtlas P49720; baseline and differential; . Genevisible P49720; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0000502; C:proteasome complex; IDA:UniProtKB; . GO GO:0005839; C:proteasome core complex; ISS:UniProtKB; . GO GO:0019774; C:proteasome core complex; beta-subunit complex; IEA:InterPro GO GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW; . GO GO:0031145; P:anaphase-promoting complex-dependent catabolic process; TAS:Reactome; . GO GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; TAS:Reactome GO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0038061; P:NIK/NF-kappaB signaling; TAS:Reactome; . GO GO:0090263; P:positive regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; TAS:Reactome; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0000209; P:protein polyubiquitination; TAS:Reactome; . GO GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; . GO GO:0043488; P:regulation of mRNA stability; TAS:Reactome; . GO GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome; . GO GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0002223; P:stimulatory C-type lectin receptor signaling pathway; TAS:Reactome; . GO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome; . GO GO:0055085; P:transmembrane transport; TAS:Reactome; . GO GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:Reactome; . GO GO:0016032; P:viral process; IEA:UniProtKB-KW; . GO GO:0060071; P:Wnt signaling pathway; planar cell polarity pathway; TAS:Reactome CDD cd03759; proteasome_beta_type_3; 1; . Gene3D 3.60.20.10; -; 1; . InterPro IPR029055; Ntn_hydrolases_N; . InterPro IPR033811; Proteasome_beta_3; . InterPro IPR016050; Proteasome_bsu_CS; . InterPro IPR001353; Proteasome_sua/b; . InterPro IPR023333; Proteasome_suB-type; . PANTHER PTHR11599:SF70; PTHR11599:SF70; 1; . Pfam PF00227; Proteasome; 1; . SUPFAM SSF56235; SSF56235; 1; . PROSITE PS00854; PROTEASOME_BETA_1; 1; . PROSITE PS51476; PROTEASOME_BETA_2; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]